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Effect of antidepressants on HIV antibodies - Online Doctor Chats

Date : 21-Feb-2012
User rating for this question
Very Good Posted in: Medicines and Side Effects
Answered by

General & Family Physician
Practicing since : 2005
Answered : 2584 Questions
User :   hello Dr.
User :   Hi
User :   I am Dr.xxxxx here
User :   I want to know, do antidepressant has any impact on HIV antibodies window period
User :   Ok
User :   No, it does not
User :   is ECLIA as good as ELISA
User :   it is a latest technique
User :   and is quite good enough
User :   as per the studies
User :   is it reliable
User :   Very much
User :   is there a need for repeat test
User :   not at all
User :   I am on Prodep 60 mg and Olimelt 10 mg
User :   ok
User :   antidepressants do not have an imact on those results
User :   you should not worry about it
User :   is there an impact of these medicines on HIV antibodies
User :   sure
User :   is ECLIA same in sensitivity as ELISA
User :   hello Dr.
User :   u there?
User :   It is quite sensitive
User :   you should not worry
User :   I want to know my HIV risk
User :   Ok
User :   I involved in non-penetrative sex with a sex worker
User :   it was genital to genital rubbing through underwear
User :   ok
User :   at no point of time my underwear or Girls panty came off
User :   I felt some moisture though
User :   is there a risk of HIV
User :   no
User :   there is no risk with this kind of exposure
User :   how.........I mean..........I want to know how
User :   because there is no blood contact
User :   or direct body fluid contact
User :   i felt some moisture............I didnt ejaculated
User :   Ok
User :   that is fine
User :   no problem with it
User :   still no risk?
User :   Right, there is no risk with it
User :   u mean 0%; 1%; 2%
User :   till date, there is no case reported
User :   so it goes towards 0
User :   ok
User :   and you have reconfirmed with tests as well
User :   so no need to worry about it
User :   my 86 days ELISA (RAPID) and 86 days ECLIA are negative
User :   fine
User :   is ELISA (RAPID) reliable
User :   that is the reason you should consider yourself riskfree
User :   yes it is
User :   also can I consider the two tests I did as conclusive
User :   Yes, you can
User :   Yes again
User :   between ELISA and ECLIA..........which is more reliable
User :   also ELISA (RAPID)
User :   Yes again
User :   i want to know which is more reliable............ELISA or ECLIA
User :   Both are good
User :   and there is no discrepancy
User :   so why do your further worry
User :   A comparative thesis is yet to be written
User :   but as of now
User :   both are reliable tests
User :   as per my knowledge
User :   and they both have same window period req or different
User :   yes
User :   it is the same
User :   required
User :   that is 6 weeks
User :   what is the difference between traditional ELISA and ELISA (Rapid)
User :   I think I myself have explained it in the previous chat
User :   Do you remember?
User :   you said something about subtypes
User :   if I am not wrong
User :   right
User :   rapid tests for the most common subtypes in the region
User :   traditional tests for all subtypes
User :   which are most common in Indian region
User :   Is ELISA (RAPID) covers those
User :   subtype C
User :   of type 1
User :   my test report says HIV-1 Antibody and HIV-2 Antibody non-reactive
User :   it checked for HIV-2 as well
User :   Yes
User :   that is right
User :   the most common one I mentioned
User :   you mean most common ones in HIV 1 and HIV 2
User :   no
User :   In India HIV 1, subtype C is most common
User :   which is tested under HIV 1
User :   when you get tested in India
User :   2 days back
User :   Ok
User :   at SRL Religare Lab
User :   both the tests together at SRL
Doctor :   ok
User :   at 86 day mark
User :   so I do not need additional testing
Doctor :   no you will not need further tests
User :   I am asking again as I am very anxious and do not want to take any chance
User :   However I will go with your advis
Doctor :   you do not need further tests. for controlling your anxiety , you need a counseling
Doctor :   it will help you to relax
Doctor :   is there anything else I can help you with?
User :   somewhere I read on internet (I forgot which site) which mentioned that antidepressant may delay the HIV antibody generation in body
Doctor :   ok. which antidepressant were you taking? and for how long you have been on it?
User :   Prodep 60 Mg since 1 month..............earlier 20 mg since few years
Doctor :   ok.
User :   Olimelt 10 Mg........1 month
Doctor :   ok
Doctor :   these might delay the response, but not to an extent that the antibodies are not been detected with tests done at 86th day
User :   ok
Doctor :   so do not worry about the test results being affected by these
User :   also my PCR DNA was not detected at 52 days
Doctor :   ok
Doctor :   it will mean that you do not have infection
User :   test done at SL
User :   SRL
Doctor :   ok
User :   sample collected on Thu but the test was run on Monday
Doctor :   ok.
User :   so any possibilty of sample going bad
Doctor :   the samples will be preserved such that there is no alteration in test
User :   I mean...................since HIV is fragile
Doctor :   do not worry about it
Doctor :   HIV virus is fragile, not the antibodies
Doctor :   and the tests that were done at 86th day were to detect the antibodies
User :   pcr dna looks for antibodies?
Doctor :   PCR DNA looks for viral replication or multiplication
Doctor :   by looking for the viral DNA
Doctor :   or the RNA
User :   so it means it checks for the virus itself
Doctor :   it checks for viral DNA or RNA, which are the genetic material of the virus
User :   any possibility of false negative DNA PCR
Doctor :   no, there is no data till now suggesting false negative for PCR DNA test
User :   ok
User :   so Dr. lookig at all my details...........including my taking antidepressant.................what do you suggest now
Doctor :   I would still say that your tests done suggests negative status
Doctor :   if you are in doubt still, you can get a HIV counseling done
Doctor :   which is done at all goverment and multispeciality centers
Doctor :   go in for a 'post test conselling' for HIV.
User :   no further test req
Doctor :   no, not needed.
Doctor :   when you go for the 'post test conselling' for HIV, be sure to give all past medical treatment details
User :   where shoud I go
User :   can you recommend someone in Mumbai
Doctor :   it is done at all goverment and multispeciality centers
Doctor :   I do not have personal references in Mumbai, since I am from Bangalore
User :   ok
Doctor :   you can go to any multispeciality hospital where HIV detection and treatment is done
Doctor :   they will have a dept called as HIV cell, you can contact them for the counselling.
User :   ok
User :   but according you.............there is nothing to worry on my part
Doctor :   yes, there is no need to worry as far as the test results are concerned
User :   ok
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