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Cutaneous amyloidosis - Online Doctor Chats

Date : 21-Feb-2012
User rating for this question
Very Good Posted in: Skin Hair and Nails
Answered by

General & Family Physician
Practicing since : 2005
Answered : 2584 Questions
User :   is macular amyloidosis curable
Doctor :   Hi
User :   Hi
Doctor :   How can I help you ?
User :   Hello, wante to knw if macular amyloidosis is curable
Doctor :   Ok.
User :   or treatable, arms and back look rather pigmnted
Doctor :   Because of the growing appreciation of the importance of pruritus as the primary trigger for the deposition of amyloid, treatment modalities are directed toward the relief of pruritus in macular amyloidosis and lichen amyloidosis.
User :   will the pigmentation go away?
User :   Theres no itching
Doctor :   It depens on person to person and is very difficult to state perfectly whether it would completely go away.
User :   can it be reduced?
Doctor :   To some amount for sure it can be redoced.
User :   what is the reatment line?
Doctor :   Medical line of Treatment :
Doctor :   1.Sedating antihistamines have been found to be moderately effective.
2.Topical dimethyl sulfoxide (DMSO), a chemical solvent, and intralesional steroids are beneficial if combined with other modalities.3. DMSO has been used with moderate success, but failures have also been reported.
4.Treatment with ultraviolet B (UV-B) light can provide symptomatic relief.
5.pulsed dye laser therapy.
User :   does it surface again ater treatment
Doctor :   Recurence is very common, and is the primary cause of concern in most cases.
User :   are peels (chemical) helpfl?
Doctor :   Surgical line of treatment : Doctor :   Usually new lines are being tried.
User :   chemcal peels like AHA TCA
Doctor :   Surgical Care : 1.Aggressive strategies proposed for the removal of amyloid include laser vaporization, dermabrasion, and excision of individual lesions. However, lesions and pruritus usually promptly recur after these treatments.
2.Electrodesiccation and curettage
3.In a prospective, side-by-side, controlled, clinical trial study, Q-switched Nd:YAG laser (532 nm and 1064 nm & before laser therapy and 8 weeks after treatment, it has been concluded that the 2 lasers are effective in reducing the degree of macular amyloidosis pigmentation, with the 532-nm laser being more effective than the 1064-nm laser.
User :   finally are there anyhealth implications?
Doctor :   Are you asking in regard to laser therapy ?
User :   No No the condtion
Doctor :   Apart from the cosmetic implications it has not been proven very pathologically or physiologically debilitating except for pruritis .
User :   Thank you Doctor
Doctor :   Thank you for ocnsulting me
Doctor :   take care
Doctor :   bye for now.
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