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Cause of decrease in mitochondrial antibodies - Online Doctor Chats

Date : 21-Feb-2012
User rating for this question
Very Good Posted in: General Health
Answered by

General & Family Physician
Practicing since : 2004
Answered : 40 Questions
User :   Hi, may I answer your health queries right now ? Please type your query here
Doctor :   Hi
Doctor :   How can I help you?
Doctor :   Are you there?
Doctor :   Are you there?
User :   hi i had 1/640 ama's in february. now theyre negative. how can this happen??
Doctor :   Do you mean ANA?
User :   no. anti mitochondrial antibodys
Doctor :   May I know the reason why this test were done?
User :   i'm pretty sick. i have hashimotos hypothyroidirm. pernicious anemia both treated (?) still sick. they diagnosed pbc after ama test now say its negative and that i don't have pbc???
Doctor :   Anti mitochondrial antibodies are auto antibodies which can be found due to various reasons including primary biliary cirrhosis.
Doctor :   A reduction in the antibody titres can mean either
Doctor :   1. a false reports
Doctor :   2. A reduction in the present immune status.
User :   i know. how come they're not there now. under what circ's can you get a false negative?
Doctor :   False negative test like mentioned can occur due to various biasis associated with the tests or due to the reduction in the present immune status.
User :   so it could be a false negative?
Doctor :   Yes, it may be a false negative test.
Doctor :   Since I do not have your other reports and I am unable to perform a physical examination, I would suggest you to
Doctor :   discuss with your treating doctor, who will be able to provide you with more information regarding the same.
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