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CRF, increased BP, fluid volume deficit - Online Doctor Chats

Date : 21-Feb-2012
User rating for this question
Excellent Posted in: Kidney Conditions
Answered by

General & Family Physician
Practicing since : 2004
Answered : 40 Questions
User :   why do patients with CRF have an increase in B/P and have fluid volume deficit?
Doctor :   Hi,
User :   Hello.
Doctor :   Kidney has a strong influence on BP via renin angiotenisin mechanism
Doctor :   also it is responsible in maintaining balance in the electrolytes like sodium , potassium chloride etc , any imbalance in sodium leads to water imbalance and thus volume disturbances
User :   so because of the hypovolemia, the heart trys to compensate for the lack of fluid and electrolytes within the system therefore the rise in b/p
Doctor :   No due to direct effect of renin and angiotensin on blood vessels , causing vasoconstriction hence increase the peripheral resistance to blood flow in effort to over come the resistance the heart pumps with pressure
User :   oh okay.
Doctor :   the electrolytes rule the water volume hence increasing r decreasing the cardiac out put which influence the force of contraction and the heart rate
User :   so why would a patient be put on Lopressor? would it be just to control the hypertension in the body or/and would it be to prevent possible CHF.
Doctor :   its for both reasons
User :   okay last question. if a patient is on Nifedipine for angina but has no symptoms of it would it soley be used to prevent angina due to the possibility of CHF.
Doctor :   yes,
Doctor :   but it has very strong effect on BP hence not used as a preventive measure
User :   so with all the drugs prescribed how is the patient not in nephrotoxicity considering the kidneys are barely functioning?
Doctor :   its advisable to use drugs which do not affect kidneys. no all drugs harm kidneys
User :   okay. Thank you very much.
Doctor :   you are welcome
Doctor :   thanks for consulting me , kindly provide your feedback
User :   will do.
Doctor :   Bye for now
Doctor :   take care
User :   thanks.
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