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Dr. Andrew Rynne
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Dr. Andrew Rynne

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Exp 50 years

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Article Home Adult and Senior Health Glanzmann Disease

Glanzmann Disease

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Glanzmann?s disease is a rare disorder of blood platelets, which results in bruising and nosebleeds. Glanzmann?s thrombasthenia is a lifelong condition for which is incurable. Patients should take precautions to avoid bleeding.

 

Glanzmann's thrombasthenia is an abnormality of the platelets. It is an extremely rare disorder of the blood, in which the platelets lack glycoprotein IIb/IIIa. Hence, no fibrinogen bridging can occur, and bleeding time is significantly prolonged.

 

Causes

Glanzmann’s disease is caused by lack of a protein required for platelets to clump together (aggregate) normally.

The condition is congenital, which means it is present from birth.

 

Symptoms

  • Abnormal menstrual periods
  • Bleeding during and after surgery
  • Bleeding gums
  • Easy bruising
  • Nosebleeds (epistaxis)
  • Prolonged bleeding with small injuries. 

 

Diagnosis

The following tests may be used to diagnose this condition:

 

Treatment:

There is no specific treatment for this disorder. Platelet transfusions may be given to patients who are having severe bleeding.

Possible complications