Methadone (also known as Symoron, Dolophine, Amidone, Methadose, Physeptone, Heptadon, Phy and many other names) is a synthetic opioid , used medically as an analgesic and a maintenance anti-addictive for use in patients with opioid dependency . It was developed in Germany in 1937. Although chemically unlike morphine or heroin , methadone acts on the same opioid receptors as these drugs, and thus has many of the same effects. Methadone is also used in managing severe chronic pain , owing to its long duration of action, extremely powerful effects, and very low cost. Methadone was introduced into the United States in 1947 by Eli Lilly and Company . Methadone is useful in the treatment of opioid dependence . It has cross-tolerance with other opioids including heroin and morphine , offering very similar effects and a long duration of effect. Oral doses of methadone can stabilise patients by mitigating opioid withdrawal syndrome. Higher doses of methadone can block the euphoric effects of heroin, morphine, and similar drugs. As a result, properly dosed methadone patients can reduce or stop altogether their use of these substances. Methadone is approved for different indications in different countries. Common is approval as an analgesic and approval for the treatment of opioid dependence. It is not intended to reduce the use of non- narcotic drugs such as methamphetamine , or alcohol . A number of pharmaceutical companies produce and distribute methadone. The racemic hydrochloride is the only form available in most countries, such as the Netherlands , Belgium , France and in the United States, as of March 2008. The tartrate and other salts of the laevorotary form ( levomethadone , with trade names including Polamidone and Heptadon) are available in Europe and elsewhere. These are more potent opioid agonists compared to racemic methadone because the dextrorotary form ( d-methadone ) is not an opioid agonist (it is an NMDA antagonist), therefore by using only the laevorotary form instead of the racemate the opioid agonist potency is doubled. Covidien (formerly Mallinckrodt ), is the major racemic methadone producer and sells bulk methadone to producers of generic preparations and distributes its own product in the form of tablets, dispersible tablets and oral concentrate under the brand name Methadose in the United States.
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Premium Questions (29)
when i masterbate afterwards it feels weird like the urge of going to the bathroom why?
i masterbated a lot since i was 15 3 times a day sometimes, when i first started i would masterbate for about 10 mintues, im now 19 and i carnt last long at all and if i havnt in a few days i cum so fast in like a 1 2 mintues from masterbating,...
I am XXXXXXX
i met an accident in last 2 months and doctors done the craniotomy operation for me,
Now i am fine my question is can i masterbate now or not?
is there any problems can occurred if i masterbate now..
i already masterbating before...
my son is 14 he masterbates 3-5 times daily and some days it could be 10 he is unable to control this problem how can i help him
hi my name is XXXXXXX for about 3 weeks now i have this achy feeling on the head of my penis and gets worsen when i get an erection and when i get an erection i seem to have to go to the washroom more, i masterbate...
Hello have been looking into adopting a family members baby due in november she has been on methadone for her whole pregnancy i was wondering the long and short term affects that has on a child? I have two young boys...
Hello I have a quistion and I'm a little worried ab it starting yesterday after masterbating the skin on my penis feels hot it's not red and there are no lesions or ne thing like that and the skin is not sore when I...
I am presetly going through diagnosis for Sulfite Allergy or Intolerance. I was wondering if calcium sulphate would be a problem?
Would you be able to simply and complexly explain why. What other Sulphates do I need to look out for?
i took a urin test and the doc said that i was postive for zanx but i have not taken any zanx the only thing i have taken is methadone an lorcet an benadrill so how is it that i would test postive for a drug that i...
hi my question is that i have been taking meathadone on and off for twelve years without seeing a doctor or having a perscription for this,i have tried so many times to do this on my own even going cold XXXXXXX for...
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Online Doctor Chat (8) - Methadone
Doctor : hi
User : hi
Doctor : how can i help u?
User : my question is
Doctor : ok pl proceed
User : can drugs be transferred through unprotected sex?
Doctor : what sort of drugs?
User : I'm talking amphetamines, barbeturates. methadone...
Doctor : Hi
Doctor :
How can i help you?
User : I have a question My cousin use to use methadone really bad. she went to the methadone clinic they had here. someone called her the otherday and told her they had wafers
User : i'm...
User : hello
User : hello
Doctor : hi
Doctor :
how can I help you?
User : yes i am going through opiod withdrawels
User : and wanted to know how to get prescribed methadone
Doctor : Methadone is a scheduled drug and needs prescription...
User : Yes I am a 38 ye old female who was on XXXXXXXX for 6 months after a heart event( doctor wont call it attack cause hearts normal and no blockages I basically overdosed on a pain killer accidentally ) I was taken off XXXXXXXX 10 days ago and...
User : i need help
Doctor : hi
Doctor : how can i help u?
User : i need to know if there is any way to get a presciption to suboxone when you are on probation
User : this is an emergency
Doctor : For Health purposes please provide these:...
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Public Forum (91) - Methadone
Hi but not this is hi means i am 21year but m not looking like 21 m looking 40 year man like a full stomach restless m doing engg but still in fst year from from three year my behavior changes m not doing any work in home just doing masteerbaing daily 7-8 times nothing doiing i cant waconltrol myself last yhree months m doing day night daily...
1 Answer
Hello Sir/ Madam. I am a college student, 22 years old and single. Being practising masterbation for 4 years now, and my penis tip has became swollen and insensitive, masterbation itself doesn t matter these days since i can t feel anything even with visual aid like porn unless i use rub it with a strong force of my hand . I am really scared...
2 Answers
here recently i have had blood in my stools sometimes i strain and sometimes not is it normal i am on methadone
My mom was on methadone for 14 years for peripheral neuropathy . She just had a pain management device put into her back on Friday. Hasn t had the methadone or any pain meds for three days. She is able to talk etc but doesn t know what she is talking about. I even took her grand kids to see her today in the assisted living home and she didnt...
1 Answer
I am very curious about the effects of combining Methadone and Xanax on an infant. A former friend of mine had a baby 2 1/2 weeks ago. The baby is still in NICU. I haven t spoken to her because I know she s lying to many people about why the baby is in the hospital. She says it s due to breathing problems because she delivered about 3 weeks...
1 Answer
24 10 mgm methadone taken in 5 day period- how lonh will they stay in your urine?
1 Answer
Hi, my husband is 27 and has stopped taking methadone . Along with the horrible side effects of withdraw, he is also experiencing blood in his stool. I have not heard of this side effect before and it is frightening. I wish we had health insurance but we can t afford it. He was on methadone for 7 months with his highest dose being 75mg. He had...
2 Answers
hi, I am on methadone and I have been unfortunately smoking crack but the thing is the last time i did it I experienced how I only could describe it as a vale of chills overwhelm my face and then body leaving my head feeling a a duel sort pulsating numbing feeling, with my heart pounding out of my chest and trouble maintaining a normal breathing...
1 Answer
what is the best time in the day to take my methadone?
What is the cost of your consultation? My 36 year old son has been a long-time alcoholic and drug abuser. During the past year he started using heroin . He s tried to detox on his own several times but always went back. He used methadone for some period, and a few months ago he went to a doctor who prescribed Suboxone . Supposedly this doctor...
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