Ezetimibe () is a drug that lowers cholesterol . It acts by decreasing cholesterol absorption in the intestine . It may be used alone (marketed as Zetia or Ezetrol), when other cholesterol-lowering medications are not tolerated, or together with statins (e.g., ezetimibe/simvastatin , marketed as Vytorin and Inegy ) when statins alone do not control cholesterol. Even though ezetimibe decreases cholesterol levels, the results of two major, high-quality clinical trials (in 2008 and 2009) showed that it did not improve clinically significant outcomes, such as major coronary events, and actually made some outcomes, such as artery wall thickness, worse . Indeed, a panel of experts concluded in 2008 that it should only be used as a last resort . In one of those studies, a head-to-head trial in 2009, a much less expensive medication (extended-release niacin ) was found to be superior. Ezetimibe actually increased the thickness of artery walls (a measurement of atherosclerosis) and caused more major cardiovascular events. However, in combination with simvastatin , a 2010 trial has shown it to be better than atorvastatin and rosuvastatin at lowering lipid levels. A significantly more positive view of the benefits of Ezetimibe is offered by Britain s NICE.
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Premium Questions (6)
Online Doctor Chat (4) - Ezetimibe
Doctor : hi
Doctor : how can i help you
User : i am having high cholestrol
Doctor : ok
Doctor : provid your age, gender
User : fig is 284
User : 65 yrs
User : female
Doctor : what is the value of cholesterol
User : 284 mf/dl
User :...
User : I was at work talking to a couple of peers and all of a sudden my brain seemed to go into slow motion. Almost like satellite TV screen when theres a storm - things were that cut up.it was over in less tha5 seconds ..I am 52 and in pretty...
Doctor : Hi
Doctor : I am Dr.
Doctor : Please go ahead with your query
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User : I am a diabetic with high cholestrol level/...
Doctor : ok
User : but it is not available in the market... can u pls confirm if it is...
User : My father has had three heart attacks in the past eight years. In 2003 he had bypass surgery, in 2005 he had stents placed, and in April of this year, he again had stents placed in the same artery which had gotten blocked.
My question is...
Public Forum (28) - Ezetimibe
1 Answer
Take Omaga 3 6 9 combo gel tabs can reduce the sgpt Take Omaga 3 6 9 combo gel tabs can reduce the sgpt
1 Answer
lately i feel my heart beating fast while im sleeping and i notice that it usually occurs during early morning around 5 am. Im on norvas for my highblood and lipitor for my cholesterol . i just started with lipitor on 15 march 2012. im wondering whether the lipitor has got anything to do with it. thank you
2 Answers
My mother has taken atorvastatin calcium (10mg)near about 4 month regularly.but now she has stop taking medicine but now reporting muscular pain on shouldar and arm ,(almost 4-5month) is this is the side effect of medicine if so then what can we do to revese the situation.Before taking this medicine she never complaints about such pain.
5 Answers
i am 51 and just had my blood work done. I am a female. my total cholestrol is 245 and my ldl is 174. My sugar is 110. I am 5ft.1 and weigh 165lbs. My doctor put me on 40mg. of simvastatin once a day, and on a diet . I have taken it for 6 days and i am going to stop taking it. The side effects are very scary from wht i am reading. I also have a...
1 Answer
i am 51 and just had my blood work done. I am a female. my total cholestrol is 245 and my ldl is 174. My sugar is 110. I am 5ft.1 and weigh 165lbs. My doctor put me on 40mg. of simvastatin once a day, and on a diet . I have taken it for 6 days and i am going to stop taking it. The side effects are very scary from wht i am reading . I also have a...
1 Answer
does anyone know any good alternatives to lipitor and or any good cardiologist or book about treatment for high cholesterol without taking any drugs? my husbands uncle started taking lipitor and months later dropped dead. now a doc is insisting my husband take it for slightly elevated...
1 Answer
is Lipitor better than zocor?
1 Answer
to help lower cholesterol?If it works it is probably expensive. I do not want to start taking Lipitor or Zocor.I try to eat right,take a asprin everyday to keep blood thin,500mg Niacin .My last reading was 235 total.
1 Answer
Dear Doctors ; is it ok to take lipitor and lipanthyl together ? or Side effects will be more? and wt is the best thing to reduce the TRG . Is there any medicine work on both Cholesterol and TGI? thanks alot
1 Answer
Is Ezetimibe for controlling cholesterol? If so, whats the side effects, and do you get body aches or leg pains?
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