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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Idiopathic Allergic Reaction

I have developed an Idiopathic allergic reaction. The last immunologist said it was caused by the Copaxone I was on. Copaxone is an immuno-modifier for MS. I developed a hypersensitive immune system. I quit taking Copaxone when I had the complete area I injected into which turned into one solid massive wheal.
This was about 8 years ago. The fallout was that I had become intolerant to eggs, milk, cheese, tomatoes, oranges, chocolate, seafood. I was not allergic to any of these foods prior to the Copaxone rejection. It was supposed to subside. I also have atypical MS which actually does gets worse from reacting to viruses, such as flu. After someone had the flu in October 2013, I instead of getting the flu, I developed chronic urticaria and at times angioedema. It has become chronic, though not as bad as it was in October - end of November, 2013. I live in the greater Vancouver area of British Columbia and would dearly love to know if there are any immunologists out there that have experience with this and if there is any immune therapy to settle my system. I am currently taking Ranitidine as an H2 antihistime and apo-hydroxizine almost daily, depending on when if flairs up. (usually first thing in the morning then again late at night.). Hoping there is something out there. I have MS but cannot tolerate immune-modifying drugs. I had PLEX as a child when I had nearly died from Henoch Schonlein Purpura and hemocytopenia purpura (age 8 - vomited blood, etc until I was only 20 lbs and was hospitalized at the time). This probably was the immune modifying setup for developing MS later in life. I have three questions: 1. Is there a really good immunologist in the vancouver area - even Washington Area? 2. Is there anywhere I can get a PLEX (plasmapheresis) treatment to calm down my system (even privately out of Province)?. 3. Is it wise for me to take Tecfidera (fumaric acid) if my immune system is already so disturbed from the copaxone. (I was at emerge 3x in Oct-Nov). had a benedryl shot at one time. Was given a prescription for an epipen on another visit. It is pretty miserable to live with. thanks for any advice, sincerely, jl
Thu, 13 Feb 2014
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  User's Response
HI
Thank for asking HCM
Stop taking the Ranitidine this is known drug that could cause the urticarial rash, instead you can take "Omeprazole 40 mg once in day" second increase the dose of hydroxyzine 20 mg three times in day will give good result, Idiopathic skin rash goes on its own later or sooner and you wont be able to notice it, hope this information helps you, have nice day.
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Suggest Treatment For Idiopathic Allergic Reaction

HI Thank for asking HCM Stop taking the Ranitidine this is known drug that could cause the urticarial rash, instead you can take Omeprazole 40 mg once in day second increase the dose of hydroxyzine 20 mg three times in day will give good result, Idiopathic skin rash goes on its own later or sooner and you wont be able to notice it, hope this information helps you, have nice day.