we are marraied about 6 yrs. in between we have 3 issues are done, but all the threes are lost after birth. 1st issue was in 2007 delivary with LCS at 24 weeks due to pre eclamsia, plasentra previa & heavy blood loss, with high BP ~260/160HG, baby live 3 days. 2nd issue was in 2009 with LCS at 34 weeks wt.-1950gm, this time also pre eclampsia , & high Bp, BP is controlled by Alpha Dopa, Lobetolol, & nicardia, But this time also baby live only 9 days, because she has sevear heart probmlem (TGA). 3rd issue was in 2012 January with LCS at 31 weeks wt.-1250 gm Due to lack of plasental water. baby expires after 21 days due to some system problem, respiratory problem, convulsion. all supports was given to her,but we loss her. all the 3 times my wife has High BP. Now we go through many medical test , all the test are normal, but our choromosomal analysis report has mine (46,XY, small Y) & my wife (46, XX, 15P+), our treating doctor say it can not harm our up coming baby. now my wife taking AMTAS 5MG, & CONCOR COR 1.25 MG medicine for BP now her bp is quite normal 130/90hg. i want to know 1) after 3 LCS again 4th LCS is safe for my wife? 2) if we decide for 4 th time pregnancy, any problem occurs due to chronosomal effect of ours to our baby? 3) is AMTAS 5 & CONCOR COR 1.25 is safe for pregnancy? 4) If not How can we controll Bp during next Pregnancy?