, your query is a bit vague . If your sister has headache associated with earache but no pathology was detected the pain may be due to migraine
. However cause in the ear and oral cavity including dental must be strictly ruled out . If she complains of noise in ear(tinnitus?) then you should visit a good audiometrist for evaluation of hearing staus & tinnitus mapping.A trial with tinnitus maskers may also be done. In order to detect migraine a detailed history of the headache including precipitating causes , aura, associated nausea vomiting
etc needs to be taken.Sibelium
a selective calcium antagonist often is found helpful in such cases but should always be taken under a doctors supervision.Hope i have been able to be of some help &your sister gets well soon.