Brief Answer:
The
lisinopril effect begins within a hour .After 48 hours you will have a steady state of your blood pressure values.
Detailed Answer:
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The lisinopril effect begins within a hour and after aproximately 12.6 hours, half of the drug is eleminated from the blood. Steady state is attained after two daily doses (every 24 hours), which means after 48 hours after drug administration .
The
amlodipine levels in blood rise gradually to peak 6 to 8h after administration. It is extensively metabolised in the liver and is slowly cleared from the blood for more than 40 hours.
So your blood pressure will not be higher than 143/90.
After 48 hours you will have a steady state of your blood pressure values.
The most common side effect of lisinopril is cough. And the most common side effect of amlodipine is swelling of the ankles or feet.
Both can cause : headache,
dizziness, depressed mood,
drowsiness, gastrointestinal symptoms such as nausea, upset stomach, vomiting or
diarrhea, skin symptoms such as mild itching or a rash .
Hope this is helpful.
Let me know if you need more clarifications. Otherwise please close and rate the answer.
Kind Regards,
Dr. Juarda