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What is your brother's age. He could be suffering from Acute Rheumatic fever
which involves heart, joints as well. Since ASLO is high he requires treatment with Penicillin. He needs to get heart check up also. The cure is with Penicillin and sometimes steroids
also needed. He can take pain killers like Paracetamol
for fever and joint pain under medical supervision but he needs Penicillin therapy after confirmation of Acute Rheumatic fever. Consult his Doctor right away otherwise he will have high chance of severe complications.