Venerable Doctor: I am a male aged 55 years who called Ben , you deal with mass media and art in professional life , in January 2013 a physician with experience in the field of rheumatology after blood analysis was made ​​at the request of his analysis of HLA - B52 , which was positive in that it concluded called Behcet s disease . My concerns have begun in August 2011 with some occasional capable in the environment of the mouth ( tongue and once again the sides of the mouth , or combined ) , really disturbing and irritating to the stress of nervousness , but we various consultations with doctors infeksioniste was not understood and was not given medical attention in time . And perhaps other signs that I had the legs mostly joint pains ( in parts of the bottom ) and associated with swelling of the joints , with the forced seeks an opinion from reumatolog doctor , who found that in the beginning I was not able simple mouth ( although not many ... times 2 times 3 for 7-10 days , then a few days rest and repeating as regular calendar ) , but the signs of the joints of the legs and analysis of HLA - B52 (which was positive in January 2013 ) , had Behcet s syndrome . Medical assistance since January 2013 ( according to the attending physician , who is the field of rheumatology ) with Medrol ( 4 - Mg ) every morning ... and colchicine ( 1 mg ) every night , and we lunch a protective Asperine ( 80 or 100 - Mg ) . This treatment uses almost interruption and I see some improvement , especially with the knees ( while communicating with each month that the following specialist doctor since January 2013) , but I still capable of oral problems because of reduced dosage or interrupted Medrol ( 4 - Mg ) for a few days or 2 - week , with resume capable in the mouth and gradually after a few days and concerns ( pain ) with legs ( especially the joints in the legs and bottom muscles occasionally some ) . The doctor added in any case Medrol dose of 4 - 6 - Mg Mg for a few days and then continue with normal Cure 4 - Mg - Mg Medrol and 1 colchicine , while year ( July - 2013) with added for a 3 -month period an additional 1 treatment once a week ( twice a day ) with Methrodoxat + folic Acid , medication that I repeated the first two months ( this is additional treatment with intermittent periods ) . What advice you dear doctor about this situation that I am ... Thank you ...