Hi! thanks for writing to us! Atrophic vaginitis and related infections, negative psychological changes are very common and rightly anticipated when a female undergoes total hysterectomy with removal of both ovaries; therefore, prevention of this post-menopausal syndrome is necessary...! That s why doctors prescribe estrogen based creams to restore normal vaginal flora and aver-all quality of life; it is safe just needs periodical PAP test/follow up! Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions. Wishing you good health.