Gilbert syndrome is a genetic condition and this autosomal recessive condition is characterized by intermittent jaundice in the absence of hemolysis or underlying liver disease. The hyperbilirubinemia (raised bilirubin levels) is mild and, by definition, less than 6 mg/dL. However, most patients exhibit levels of less than 3 mg/dL; bilirubin levels occasionally may be normal in as many as one third of patients. It is the most common inherited cause of unconjugated hyperbilirubinemia, Gilbert syndrome is a benign condition with no associated morbidity or mortality. Mild jaundice is present intermittently in some individuals, but no other abnormal physical examination findings are evident. The common causes for this syndrome are are dehydration, fasting, Intercurrent illness, such as a viral infection, Menstrual periods, Stress, such as trauma and overexertion. The most important aspect of treatment once the diagnosis is established is reassurance. After diagnosis is made it is educated to the patient about its benign nature. It has an excellent prognosis and is associated with normal life expectancy, which must be made perfectly clear to the patient. Diet is normal. No activity restrictions are necessary.