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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does The Presence Of Giant Platelets Mean?

My blood test results state CBC Giant Platelets are present. What does this mean? I am a 68 year old woman with diabetes, polymyalgia rheumatica, hypertrophic cardiomyopathy, last year had a heart attack (mild), stroke and migraine that lasted more than 72-hours, even with hospital ER treatment (can't remember exact name of diagnosis). I am 5 ft. in. and weigh 180. I also have Charcot Joint disease and am scheduled to have my left foot operated on to remove bone that has caused a sore on the sole of my foot - had osteomylitis last year, and had my right foot operated on. I'd appreciate any info you can give me. Sharon
Fri, 24 Oct 2014
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Diabetologist 's  Response
Hi,
Thanks for asking.
Based on your query, my opinion is as follows.
1. Giant platelets do not have any significance with normal platelet count and bleeding time.
2. Do not worry about giant platelets. Most commonly secondary to Vit B12 deficiency.
3. Take Vit B12 supplements and keep checking your platelet count monthly once. If its normal. Not to worry. You can go for surgery, no problem.
Hope it helps.
Any further queries, happy to help again.
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What Does The Presence Of Giant Platelets Mean?

Hi, Thanks for asking. Based on your query, my opinion is as follows. 1. Giant platelets do not have any significance with normal platelet count and bleeding time. 2. Do not worry about giant platelets. Most commonly secondary to Vit B12 deficiency. 3. Take Vit B12 supplements and keep checking your platelet count monthly once. If its normal. Not to worry. You can go for surgery, no problem. Hope it helps. Any further queries, happy to help again.