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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does Presence Of Mast Cell In CBC Test Indicate?

Hi, I have a 14 yr old son who has been being followed by a hematologist for 9 months for mild thrombocytopenia and mild neutropenia. His only clinical symptom is fatigue. A BMB has not been performed. His DR thinks its either ITP, or less likely, familial or a bone marrow failure. I am a Med tech and I occasionally check his CBC. Last time I looked at his smear, I found a mast cell. Is this significant? Could this be a clue to what's going on with him? Should I wait 2 more months for his next appointment, or go in earlier? Thank you.
Thu, 29 Jan 2015
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Pathologist and Microbiologist 's  Response
Hello and welcome to HCM,
The normal percentage for a mast cell or basophil on peripheral blood smear is 0-1% and the absolute number varies from 0-100 cells per cubic millimeter.
Thus, it is normal to find a single mast cell or basophil on peripheral blood smear.
There is nothing to worry about it.
You can consult your hematologist for treatment of ITP without any worry.


Thanks and take care
'DR Shailja Puri
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What Does Presence Of Mast Cell In CBC Test Indicate?

Hello and welcome to HCM, The normal percentage for a mast cell or basophil on peripheral blood smear is 0-1% and the absolute number varies from 0-100 cells per cubic millimeter. Thus, it is normal to find a single mast cell or basophil on peripheral blood smear. There is nothing to worry about it. You can consult your hematologist for treatment of ITP without any worry. Thanks and take care DR Shailja Puri