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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does Non Reactive VDRL And TPHA Indicate After Syphilis Treatment?

Hi doc, I had syphilis before and it's already been few months after my treatment, the results for both VDRL and TPHA are non-reactive. What concern me most is that TPHA should always be negative no? I'm not sure whether this is lab mistakes or I have strong antibody as explained by one of the hospital's staff.
Fri, 30 May 2014
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Pathologist and Microbiologist 's  Response
Hello and welcome to HCM,
The VDRL and TPHA are based on antigen-antibody reaction.
Any antigen-antibody test is reported as reactive or non-reactive.
Some laboratories report the test as positive or negative.
Thus, non-reactive VDRL and TPHA tests suggest absence of syphilis or some infection.
The infection has been treated by antibiotic.

Thanks and take care
Dr Shailja P Wahal

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What Does Non Reactive VDRL And TPHA Indicate After Syphilis Treatment?

Hello and welcome to HCM, The VDRL and TPHA are based on antigen-antibody reaction. Any antigen-antibody test is reported as reactive or non-reactive. Some laboratories report the test as positive or negative. Thus, non-reactive VDRL and TPHA tests suggest absence of syphilis or some infection. The infection has been treated by antibiotic. Thanks and take care Dr Shailja P Wahal