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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Could Cause Reduced WBC While Having Sickle Cell Trait And Probable Diabetes?

Hi, I am a 32 male and I have a sickle cell trait and maybe a type 2 diabetes I have a problem my WBC is 2.9 I jest get the lap report today. Before 3 months they were 3.4. I have seen oncology last Jan. 14 and he said the A1C cannot be tight since I have sickle cell trait and he requested so lap work Hepatitis, p12 and both were fine but my wbc is still low. I don not know what to do. so can you please give your advise. Regards,,
Mon, 29 Dec 2014
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Pathologist and Microbiologist,  's  Response
Hello and welcome to HCM,
Sickle cell trait affects the hemoglobin chains in red blood cells and is no way related to white blood cells.
Thus, low white blood cells are not caused by sickle cell trait.
Low white blood cell counts are seen in cases of bone marrow depression or in cases of severe infections.
Other blood parameters also have to be assessed to determine the cause of low white blood cell counts.
Infections can also cause depression in white blood celll counts thus, focus of infection has also to be found.
I suggest you to consult your physician or preferably a hematologist for clinical assessment and thus management.

Thanks and take care
Dr Shailja P Wahal


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What Could Cause Reduced WBC While Having Sickle Cell Trait And Probable Diabetes?

Hello and welcome to HCM, Sickle cell trait affects the hemoglobin chains in red blood cells and is no way related to white blood cells. Thus, low white blood cells are not caused by sickle cell trait. Low white blood cell counts are seen in cases of bone marrow depression or in cases of severe infections. Other blood parameters also have to be assessed to determine the cause of low white blood cell counts. Infections can also cause depression in white blood celll counts thus, focus of infection has also to be found. I suggest you to consult your physician or preferably a hematologist for clinical assessment and thus management. Thanks and take care Dr Shailja P Wahal