Hello, Have been on prednisone for five months now, frustrated that doctors have been unable to make a diagnosis. Have seen family physision, 2 allergists, and 2 rhuemotologists. First seen in emegency ,July 2011. Unable to breath and swollen eyes, red face . Thought I was having an allergic reaction to something? Was put on prednisone at that time and every time I try to wean off the medication, the inability to breath comes back, worse every time. My neck turns red and has raised hives, as well as my face turns swolen red with hives and itchy. All blood tests have come back normal, thyroid normal, not lupus or an autoimmune disease....although that is what my family doctor suspects. I have had high blood pressure for 2 years but is under control with medication. Lately, my heart rate has been higher than normal, sometimes waking up in the night with racing heartbeat. My weight has stayed the same dispite the prednisone, I am very active and eat well, work out daily. Have recently seen a cardiologist also, ECG normal and echocardiogram normal. Have had much trouble with indigestion, when weaning off the prednisone, I cant seem to go right off the prednisone as all the symptoms seem to flare back up when I get down to about 5mg a day. Help..... Selina