Hallow Dear, Pregnancy test on urine is reliable after about a week of missed period; earlier these tests can report false negative results. However, since you have repeated the test twice, it is likely that later test was done after about a week of missed period. If not you may repeat the test on overnight early morning first urine sample after 4 more days. If this test also reports negative, you are not pregnant. There are multiple causes apart from pregnancy for missing a period. However, from your history, it appears that you are under tremendous depression and anxiety. Your feeling for permanent change in the body also seems to be out of anxious feeling. This is one of the very important and common causes of missing a period; and then irregular menses subsequently. Please report to some counsellor/psychiatrist with your anxiety/depression issue for effective management. Hormonal imbalance also can cause irregularity in the menses. Please report to your Gynaecologist for thorough investigations and management. Meanwhile you may take some progestational preparation like Deviry for 5 days and then hope for the withdrawal bleeding with 4-7 days after that, if you are not pregnant. This medicine should be taken with a Gynaecologist s advice only. I hope this helps you. Dr. Nishikant Shrotri