What could cause skin to peel on palms of my hands and itching? I started using gloves to wash dishes so as not to touch dish soap, stopped using my usual hand lotion. No change in any soaps. I used Gold Bond lotion which did not help. I went to a local pharmacy and they suggested Eucerin which did not help. I do have psoriasis on other areas but this peeling skin is different, but I did try the cream I have for that but it didn t help. Sometimes I ll notice a brown spot like a pimple which lasts a few days then fades away. This is only on the palms of my hands. Thank you.