Hi welcome to health care majic My name is Dr Ehsan and I have gone through your query. There are certain effects of meth on Life style of the Users. which are basically by interacting via a body s chemical known as Dopamine, meth increases the body s dopamine level there by leads to certain effects like A feeling of well being (Euphoria), decreased appetite sleep disturbance Mood swings Increased heart rate and blood pressure tremors and convulsions you have mentioned that he also did Poppers which means which is also amyl nitrate which causes headaches and burns if spilled on skin. Some of these adverse changes may get better over time, but for some users, they may not. it is best to avoid using it altogether. hope he recovers from this otherwise seek medical attension by visiting your GP. Hope this may help you. Let me know if anything not clear. Thanks.