My wife has Parkinson s - well controlled with Sinemet. Associated with Parkinson s she has a neurological blood pressure problem none of the neurologists we have worked with these past 4 years has found an answer. Her pressure can vary from 220/110 to 55/30. She is now passing out at every attempt to stand. The pressure even in the doctor s office can drop 100 sys and 25 dys in 30 seconds from lying to standing. She is also on Fludrocortisone and Donepezil amd gabopentin (for restless legs). The specialists have concluded that the BP fluctuation is a neurological problem but none of them have found a way to control (a lot of experimental drugs such as Azor and use of Pressure stockings) None have had an effect. Are there other sources for help. She is currently essentially bed fast, changing positions only with someone at her side to lower her head to the floor.