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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Elevated TSH And TPO Values?

my anti tpo level is 1300.how should react.my age is 29 female.earlier my tsh was 29.5.then i had thyronorm 75.after 3 months tsh level was 0.2.In between i continue same medicine,but missed my dose 6, 7 times.after 3 months my tsh level was 12 and tpo 1300.my weight is 48 kg.I have lost or gain weight.It is consistant
Thu, 20 Oct 2016
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Endocrinologist 's  Response
Hello,
I read carefully your report and understood your concern.
High AntiTpo antibodies are consistent with an autoimmune disease called Hashimoto thyroiditis. It is a chronic disease and the antibodies will remain high, they destruct the thyroid tissue making the thyroid gland unable to produce enough hormones.
The treatment consists in substituting the hormone and maintaining normal level of TSH.
There is no treatment to lower the antibodies.
So, all you have to do is to take the thyronorm regularly, every morning with empty stomach and check the TSH after 6 weeks until you find the appropriate dose. Once you have found it than a 6 months control is recommended.
For the moment i would recommend 62 mcg (1 day 50mcg and one 1 day 75 mcg).
Hope the information is helpful. Do not hesitate to ask if you will have further questions in the future.
Kind regards,
Dr.Mirjeta
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What Causes Elevated TSH And TPO Values?

Hello, I read carefully your report and understood your concern. High AntiTpo antibodies are consistent with an autoimmune disease called Hashimoto thyroiditis. It is a chronic disease and the antibodies will remain high, they destruct the thyroid tissue making the thyroid gland unable to produce enough hormones. The treatment consists in substituting the hormone and maintaining normal level of TSH. There is no treatment to lower the antibodies. So, all you have to do is to take the thyronorm regularly, every morning with empty stomach and check the TSH after 6 weeks until you find the appropriate dose. Once you have found it than a 6 months control is recommended. For the moment i would recommend 62 mcg (1 day 50mcg and one 1 day 75 mcg). Hope the information is helpful. Do not hesitate to ask if you will have further questions in the future. Kind regards, Dr.Mirjeta