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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Elevated SGPT And SGOT Levels?

I am a diabetic of 38 years. My blood work today showed the sgpt(42)and sgot (46) were slightly elevated. Everything else was normal. My cholesterol was 195, my triglyceride was 59, my hdl was 79, and ldl was 104. Could it possibly be a diet issue. I have been eating more fatty foods than normal, and have craved and eaten coconut lately. I am 54, through menopause and everything seems to be topsy turvy. My mom died 2 years ago with cirrosis of the liver and she never drank a drop in her life. I am not a drinker of alcoholic beverages either. Advise please!
Thu, 24 Jul 2014
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Internal Medicine Specialist 's  Response
Thank you for the query.
As per history, you a 54yrs old lady (through menopause), a long term diabetic (around 38yrs) with slightly deranged Liver enzymes. Your lipid profile is within acceptable limits.
Your profile is similar to a condition known as Non-Alcoholic fatty liver disease (NAFLD), which is common in diabetics (though the liver enzymes are more deranged in this condition). Consumption of fatty diet, may indeed be a cause. It is recommended to avoid refined carbohydrates, saturated fat and carbonated drinks. High fibre diet is advised. It is commendable that you do not consume alcohol.
Cirrhosis, may not always be due to consumption of alcohol. A number of other conditions can cause Cirrhosis like - Chronic Hepatitis B/C infection, Autoimmune hepatitis, NAFLD, Wilson's disease etc. Without further information, it will be difficult to comment as to why she developed Cirrhosis.
I would advise you to repeat your liver function test after a month, and if your enzymes are persistantly elevated or on the rising trend, please do visit your physician. Some investigations like USG upper abdomen and some blood tests may be needed.
Hope this helps you out.
Regards,
Dr. Ayusmati Thakur
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What Causes Elevated SGPT And SGOT Levels?

Thank you for the query. As per history, you a 54yrs old lady (through menopause), a long term diabetic (around 38yrs) with slightly deranged Liver enzymes. Your lipid profile is within acceptable limits. Your profile is similar to a condition known as Non-Alcoholic fatty liver disease (NAFLD), which is common in diabetics (though the liver enzymes are more deranged in this condition). Consumption of fatty diet, may indeed be a cause. It is recommended to avoid refined carbohydrates, saturated fat and carbonated drinks. High fibre diet is advised. It is commendable that you do not consume alcohol. Cirrhosis, may not always be due to consumption of alcohol. A number of other conditions can cause Cirrhosis like - Chronic Hepatitis B/C infection, Autoimmune hepatitis, NAFLD, Wilson s disease etc. Without further information, it will be difficult to comment as to why she developed Cirrhosis. I would advise you to repeat your liver function test after a month, and if your enzymes are persistantly elevated or on the rising trend, please do visit your physician. Some investigations like USG upper abdomen and some blood tests may be needed. Hope this helps you out. Regards, Dr. Ayusmati Thakur