I am diabetic and y blood sugar has been real high over the past few days. When I say real high I mean over 500. I drank a lot of water and urinated very frequently. I finally got it to start coming down however that night I had horrible cramps in my thighs and in my ankles. I had this 1 other time and it took a few days to get over it. It seems to help if I drink some Gatorade and then I seem fine. The next day I had extreme tiredness even though I had gotten my sugar down to 140. I didn t really want to eat and I drank very little water only to take my pills because I was just too tired to get out of bed. I have not ever had this reaction. I am feeling ok today. I am getting a little tired but that is really normal. Yesterday I could not stay awake.