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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Abnormal Behavior While On Pristiq?

My husband has been taking zoloft and his doctor just put him on pristiq. His 1st dose together was today and he acts like he is drunk. Is this normal? The doctor is also trying to get him off the Zoloft. But told him to take them together and slowly wien himself off of the Zoloft.
Mon, 27 Oct 2014
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Psychiatrist 's  Response
Hi.

I understand your concern.

Zoloft contain sertraline and pristiq contain des venlaflaxin.

Both are antidepressant.
Use in combination in depression.
Sometimes in intial therapy it is possible due to sedative effect he behave like drunken.

But gradually sedative effect of these drug will decrease.

Look for other drug along with these two.

Consult psychiatrist if it will persist.

Still if you have a query then feel free to ask.

Happy to help you further.

Thank you.

Take care.
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What Causes Abnormal Behavior While On Pristiq?

Hi. I understand your concern. Zoloft contain sertraline and pristiq contain des venlaflaxin. Both are antidepressant. Use in combination in depression. Sometimes in intial therapy it is possible due to sedative effect he behave like drunken. But gradually sedative effect of these drug will decrease. Look for other drug along with these two. Consult psychiatrist if it will persist. Still if you have a query then feel free to ask. Happy to help you further. Thank you. Take care.