Hi. Thanks for your query. Read and understood the history about your wife. You mentioning since who long is she suffering and any other associate medical problems does she have would have helped me a bot. All the symptoms of nausea, gas. flatulence and chills, pain between the shoulder blades can be related to the diagnosed gall stone disease. But not the lower abdominal pain. Gall stones cause pain in the upper right side of the abdomen. I would advise her the following: Fresh ultrasonography of the abdomen. Physical examination and clinical evaluation by a Gynecologist and a General Surgeon can help to get a probable cause of all the symptoms. Test of blood- particularly for liver function tests, urine and stool. Once the proper diagnosis is made you can take her for surgery of the gall bladder and also see the lower abdomen on exploration by Laparoscopy and Laparotomy.