Well the patient is in a condition where medical help
is must. things are worsening probably because she is down with spirits. Something bad must have happened to her and on which she is dwelling from long. The depressed spirits are discouraging her day by day. In my opinion along with the current treatment, which of course is must to preserve the vital organs and functions of the body, you shall take the help of some Psychoanalyst.
Once she will start taking interest in her daily schedule she will start improving and all the existing medical problems will start improving gradually. Morale and confidence are very essential for an healthy existence so we need to work on it. The only way is to make her speak with all her feelings and expressions.
In nutshell kindly carry on with the treatment we should not leave hope and consult a psychoanalyst for the state of mind.
Wish you health and prosperity