Dear Ma am Thanks for posting your query on HCM. I appreciate your concern for the safety profile for Actonel. Actonel on long term use can cause ulcer or inflammation in the food pipe (oesophagus) producing severe heart burn, difficulty in swallowing, abdominal pain, it is also associated with bone loss (osteonecrosis) in the jaw. If you have any acidity related stomach upset it is better to avoid it. Wait for your next appointment. Meanwhile you can take vit D with calcium supplements which are available over the counter. Hope this information helps you. Wishing you a good health.