Hi. Thanks for your query. Noted the history and understood your concerns. There are no side effects of colonoscopy unless perforated by the scope or the air inflated. Other few things that colonoscopy can cause are due to cleansing like disturbed GI bacterial flora, gases, loose stools for a few days, discomfort and so on. CRPS is not caused by colonoscopy for sure. If the Rheumatologist is unable to help you, you may turn up to another one for second opinion and further management. Complex regional pain syndrome (CRPS) is a chronic pain condition most often affecting one of the limbs (arms, legs, hands, or feet), usually after an injury or trauma to that limb. CRPS is believed to be caused by damage to, or malfunction of, the peripheral and central nervous systems. The central nervous system is composed of the brain and spinal cord, and the peripheral nervous system involves nerve signaling from the brain and spinal cord to the rest of the body. CRPS is characterized by prolonged or excessive pain and mild or dramatic changes in skin color, temperature, and/or swelling in the affected area. Hence it is complex disease and needs multi-specialty approach.