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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Side Effects Of Neoral?

Hi doctor i want to ask about the drug neoral for a hypertensive patient the doctor prescribed it to her . she has protinurea lower limb and face edema .is it good? and i want to know also if it has interaction with atorvastatin and amlodipine and zyloric. Also i want to know about the side effects because i read hat it is immunosuppressant. Thanx.
Fri, 18 Nov 2016
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Diabetologist,  's  Response
Hi,
Neoral (Cyclosporine) can cause hypertension and also has a toxic effect on kidneys. Proteinuria, lower limb and facial edema is pointing towards some kind of kidney involvement. I would advice you to consult your physician immediately.
Yes, Neoral(cyclosporine) is an immunosuppressant drug.
And regarding interactions, following points may be noted.
1) I would be very cautious to use combination of atorvastain and cyclosporine. I would limit the dose of atorvastain to 10mg/day if the combination is essential for the patient.
2) I would also be cautious with amlodipine and cyclosporine combination as amlodpine can increase the effects of cyclosporine.
3) Zyloric (allopurinol) can also cause a minor increase in levels of cyclosporine.
I hope the above information helps you in discussing the management with your physician. Thanks.
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What Are The Side Effects Of Neoral?

Hi, Neoral (Cyclosporine) can cause hypertension and also has a toxic effect on kidneys. Proteinuria, lower limb and facial edema is pointing towards some kind of kidney involvement. I would advice you to consult your physician immediately. Yes, Neoral(cyclosporine) is an immunosuppressant drug. And regarding interactions, following points may be noted. 1) I would be very cautious to use combination of atorvastain and cyclosporine. I would limit the dose of atorvastain to 10mg/day if the combination is essential for the patient. 2) I would also be cautious with amlodipine and cyclosporine combination as amlodpine can increase the effects of cyclosporine. 3) Zyloric (allopurinol) can also cause a minor increase in levels of cyclosporine. I hope the above information helps you in discussing the management with your physician. Thanks.