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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are Effects Of Tylenol Overdose?

hi my boyfriend took a small handful of Tylenol he thinks they were Tylenol pm. he does not remember how many he took though. Its only been about an hour he refuses to go the hospital and wont tell anyone at home. Hes 16 and weighs around 130. My questions are how many pills can be taken at one time before it can become lethal and what are the signs of overdose?
Mon, 6 Oct 2014
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Internal Medicine Specialist,  's  Response
Hello,

Tylenol ( Paracetamol) overdose is a medical emergency and he should attend the emergency if the number of tablets taken is unknown and have a gastric lavage to remove it. The minimum lethal dose is about 7.5 grams.
The first symptoms of overdose usually begin several hours after ingestion, with nausea, vomiting, sweating, and pain as acute liver failure starts. People who take overdoses of paracetamol do not fall asleep or lose consciousness . The process of dying from an overdose usually takes three to five days.
Tylenol PM in addition contains Diphenhydramine which is a sedating and will add to the toxicity of the paracetamol.
Hope he is well.
Dr. Noble Zachariah
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What Are Effects Of Tylenol Overdose?

Hello, Tylenol ( Paracetamol) overdose is a medical emergency and he should attend the emergency if the number of tablets taken is unknown and have a gastric lavage to remove it. The minimum lethal dose is about 7.5 grams. The first symptoms of overdose usually begin several hours after ingestion, with nausea, vomiting, sweating, and pain as acute liver failure starts. People who take overdoses of paracetamol do not fall asleep or lose consciousness . The process of dying from an overdose usually takes three to five days. Tylenol PM in addition contains Diphenhydramine which is a sedating and will add to the toxicity of the paracetamol. Hope he is well. Dr. Noble Zachariah