my just born son had infection on 2 days of birth with Hypoxia , convulations , Metabolism (glucose 17) and Sepsis and got fits. He had some leisons on the brain and he has got his brain damaged. Past 2 days he is getting jerks on the shoulder and we have admitted him on 26 jan 2014. The antibiotic treatment was not successful . His brain in second MRI is showed permanant damage. will this lead to any abnormality ? and will he get fits in future ? Doc say likely fits in future and for abnormality wait and see . i am anxious??? Treatment summary This term/AGA, male neonate , delivered on 07/12/2013 , delivered on 07/12/2013 by LSCS (Post datism with oligohydraamnios) , had cried at birth with a birth weight of 2.7 Kgs. Baby was brought on day 4 of life with convulsions and hypoglycaemia and seizures. He was given ventilator support, Fluid boluses was given , followed by maintainace IV fluids with which blood glucose came under control. Baby had increased CRP with decreased platelet count and deranged coagulation profile. Sepsis was suspected. IV antibiotics was given. Baby was also given platelets and FFP transfusion. In V/o Hypocalcaemia, IC calcium was given. Baby had decreased urine output and increased S. Creatinine on admission which improved with IV fluids. With the above management, baby improved and was extubated on day 4 of stay. He required supplemental oxygen for the next few days. In v/o episodes of seizures followed by decreased activity, EEG done, which showed parieto-occipetal discharges. Phenobarbitone was given as per advice of Neurologist, Dr. Shekhar Patil. USG cranium was normal. CSF analysis done after platelet count and coagulopathy normalised, showed increased protein. MRI brain was done which showed bilateral cortical fronto parietal and temporal cortical hyperdeintensities with underlying mild diffuse oedema. There is restricted diffusion seen in the bilateral fronto parietal white matter with restricted diffusion in the corpus callosum. This could represent acute brain injury with cytotoxic oedema. Dr. Shekhar Patil opinion taken, he suggested leukoencephalopathy due to sepsis? Hypoxia? Metabolism. To repeat MRI brain at 6 weeks of Age (01/02/2014). IV antibiotics given for 21 days. Baby’s neurosonography done at discharge was normal. Baby taking breast feed well. Baby is discharged.