The dosage of the medication can be increased if there is no response, but only under medical supervision. The maximum recommended dose is usually 1500 mg. but studies have shown a response to be seen at 2000 mg. dose when the 1500 mg. dosage has failed. Also, maintain a healthy BMI and regular exercise. I would not suggest consumption of several medications or nutritional supplements at the same time, but prenatal vitamins
may be taken. Hope your query has been answered. Wish you good health.