Hello Good Evening, You said that you have PCOS (Polycystic ovary syndrome). PCOS produces symptoms in approximately 5% to 10% of women of reproductive age (12–45 years old). It is thought to be one of the leading causes of female sub-fertility and the most frequent endocrine problem in women of reproductive age. The principal features are anovulation, resulting in irregular menstruation, amenorrhea, ovulation-related infertility, and polycystic ovaries; excessive amounts or effects of androgenic (masculinizing) hormones, resulting in acne and hirsutism; and insulin resistance, often associated with obesity, Type 2 diabetes, and high cholesterol levels. The symptoms and severity of the syndrome vary greatly among affected women. In PCOS, there is a so-called follicular arrest , i.e., several follicles develop to a size of 5–7 mm, but not further. No single follicle reaches the preovulatory size (16 mm or more) but you have 16 mm or more, so do not get tensed. Every cycle can not be the same, due to many physiological and hormonal effects, so keep patience and continue on treatment. So keep in touch with your gynecologist for continuation of the treatment and monitoring. Regards, Dr. Naresh Jain.