Hello. Welcome to HCM, The sure and definite treatment for gall stones is surgery. Long standing gall stones are very much prone to infection, empyma (severe inflammation and pus like formation) and perforation of gall bladder. These complications can in turn affect other intraabdominal organs by leakage of bile. In the long run, gall stones may even be complicated by malignant change in gall bladder. Now the better part of the story is that gall stone surgery is a very standard procedure, and in expert hands has minimal risk and complications with a smooth pain free life later. The advice would be to go in for surgery at good centre without fear and with good hope. All the best.