Perimenopausal irregularity of menstrual cycles for 5years should be taken seriously and its better to get it investigated with an endometrial biopsy
as the earlier a diagnosis is made the better it is. Incase your report is normal, you can be relaxed and wait for your menopause
As you mentioned that you had a bleeding episode after a gap of 11months which is almost like a postmenopausal bleeding and any kind of postmenopausal bleeding should be investigated. Menoapuse is considered when there are no menses for a period of 12mnths in any female of your age.
Also you have mentioned you have an endometrial thickness of 16mm which is definitely more than what should be at your age. As after menopause endometrial thickness of more than 4mm with irregular bleeding should be investigated. You also have history of endometriosis
which is a hyperestrogenic state and can cause endometrial hyperplasia
) as well.
Its not necessary your bleeding is due to cancer, it can be due to endometrial hyperplasia which can be simple, complex or atypical. Only the atypical ones have to be surgically managed. Simple hyperplasia can be treated with drugs like meprate
But i would definitely advise you to go ahead for an endometrial biopsy. Also get a PAP's smear done if you dont have one as yet.