These symptoms could be due to vascular occlusion around your thigh or knee.
Colour Doppler may help in diagnosis.
You may need clinical examination to rule out this.
As you have taken many medicine and wound is not responding you need combined approach with increasing internal immunity by diet and herbs,daily dressing of wound and treating underlying cause.
Many of my patients get relief by yoga
pranayama and sudarshan kriya so you can also start that.
Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries. For further query you can contact directly on my profile http://doctor.healthcaremagic.com/doctors/dr-vaibhav-gandhi/63503
Wishing you good health.