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You have not mentioned age, gender, personal history or other morbidity.
Several possibilities have to be considered...
Left heart failure
will be the first thing to consider and exclude
is highly probable
Allergy to pillow / sheets / air-conditioning - may worsen asthma
X-ray chest / Lung function (Spirometry
) / EKG /HOLTER / ECHOcardiogram
/ TMT (exercise EKG) / LABORATORY work-up – may all be necessary for further assessment and assistance.
The treating doctor may suggest them depending on need, based on his assessment of the situation.
Wishing speedy recovery