Hi, thanks for using healthcare magic Chest pain can be related to any structure in the chest from the skin inwards. Skin- there can be pain related to some rashes such as shingles Soft tissue- there can be pain related to the muscular tissue in the chest from inflammation or injury Bones- costochondritis is inflammation where the ribs meet the sternum, this can be associated with pain which is generally worse with movement. This pain can be severe Esophagus- this structure can cause pain in persons who have gastroesophageal reflux disease or in cases of esophageal spasm Lungs- pain can be related to the lungs in conditions such as pleurits ( inflammation of the lining of the lung), pneumonia, pulmonary embolism ( blockage of a blood vessel in the lung) Heart disease- normally this pain occurs on activity when the heart is working its hardest and resolves on rest. It may be associated with shortness of breath, palpitations. It would normally be related to decrease blood supply to some part of the heart. If the ECG and tread mill were normal it is unlikely that you have heart disease. Chest pain can also be related to anxiety.In this case shortness of breath and palpitations can also occur along with the chest pain. I hope this helps