Hi More details are needed like whether your sore throat is preceded by cold, whether you have heartburn etc to determine cause of your throat pain. You may be having acute pharyngitis or acute tonsillitis as these are common. It indicates inflammation of throat or tonsils. This may be due to infection (viral or bacterial) or due to irritation of throat by acid reflux (acid coming up the food pipe). By examination it is possible to differentiate between pharyngitis and tonsillitis. If no other problems are there then sore throat is commonly due to viral infection. You have written not able to spit out nor take it in. Are you able to swallow liquids? If not you may need intravenous fluids to prevent dehydration. You have written doctor prescribed medicines. But have you started taking them? If you have already started continue the same. If not do the following: Take as much as warm liquids You can take Combiflam for pain, can do throat gargles with Wokaine But hold on with Azithral (antibiotic). You can start it if your throat pain is increasing (suggestive of secondary bacterial infection) After that if your problem persists consult an ENT specialist Wish you good health.