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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Teenager. On Encorte Chrono For Juvenile Myoclonic Epilepsy. Any Side Effects?

hi i am taking encorate chrono 300 mg from yesterday because my doctor said that i have juvenile myoclonic epilepsy. I am male and my age is 19. Doctor advised me to take the medicine 2 times/day for life long. So i want to know that is there side effects of this? and if it is there so what to do for that? Thanks.
Requesting to reply please.
Tue, 3 Sep 2013
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Psychiatrist 's  Response
Thank you for your query. Encorate chrono is a common drug given for your condition. It contains Sodium valproate and Valproic acid.
It is a comparatively newer and relatively safer anti epileptic (compared to older ones like Eptoin, Gardenal etc.)
Common side effects are sedation, gastritis, alopecia (falling of hair), mild hepatic dysfunction, confusion, weight gain, Polycystic Ovarian Disease (only in females).
Some rare, but severe side effects include hepatitis,pancreatitis, bone marrow suppression, rashes, vasculitis.
However, you need not to worry as your dose is quite low. My patients whom I prescribe Encorate chrono, I ask for a liver function test done at baseline (i.e. before starting medication), at three months,and yearly thereafter. I also ask my patients to monitor body weight every 3 months. I also prescribe Folic acid along with valproate,particularly in my female patients. And I warn them about the signs of toxicity or overdose, which includes blurred vision, difficulty in speech (dysarthria), tremors, gait abnormality, confusion etc. And I ask them to contact me immediately in case any of these appears.
you should be in touch with your doctor regularly during treatment at an interval convenient to you both.
hope I've been able to satisfy your query. best of luck.
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Internal Medicine Specialist Dr. Venkat Sivayogi 's  Response
Hi,
welcome to HCM,

Every drug will have some side effects and your prescription drug Encorate chrono do have side effects. But When you compare the side effects vs your response for the treatment actually matters. If the situation demands to reduce your disease prognosis you have use that medicine.

So, to reduce the side effects, what you hvae to do is discuus with your neurologist to reduce dose of your medication, if you are symptom free for a long time. Thats all

regards,
Dr.sivayogi

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Teenager. On Encorte Chrono For Juvenile Myoclonic Epilepsy. Any Side Effects?

Thank you for your query. Encorate chrono is a common drug given for your condition. It contains Sodium valproate and Valproic acid. It is a comparatively newer and relatively safer anti epileptic (compared to older ones like Eptoin, Gardenal etc.) Common side effects are sedation, gastritis, alopecia (falling of hair), mild hepatic dysfunction, confusion, weight gain, Polycystic Ovarian Disease (only in females). Some rare, but severe side effects include hepatitis,pancreatitis, bone marrow suppression, rashes, vasculitis. However, you need not to worry as your dose is quite low. My patients whom I prescribe Encorate chrono, I ask for a liver function test done at baseline (i.e. before starting medication), at three months,and yearly thereafter. I also ask my patients to monitor body weight every 3 months. I also prescribe Folic acid along with valproate,particularly in my female patients. And I warn them about the signs of toxicity or overdose, which includes blurred vision, difficulty in speech (dysarthria), tremors, gait abnormality, confusion etc. And I ask them to contact me immediately in case any of these appears. you should be in touch with your doctor regularly during treatment at an interval convenient to you both. hope I ve been able to satisfy your query. best of luck.