HI thanks for your query some fact about Methadone Methadone is mainly used in the treatment of opioid dependence. It has cross-tolerance (tolerance to similar drugs) with other opioids including heroin and morphine, and offers very similar effects, but a longer duration of effect. Oral doses of methadone can stabilise patients by mitigating or making more tolerable; opioid withdrawal syndrome. Higher doses of methadone can block the euphoric effects of heroin, morphine, and similar drugs. As a result, properly dosed methadone patients can reduce or stop altogether their use of these substances. Methadone is approved for different indications in different countries. Common is approval as an analgesic and approval for the treatment of opioid dependence. It is not intended to reduce the use of non-opioid drugs such as methamphetamine, or alcohol. side effect of methadone- Thrombus Hypoventilation Constipation Extreme sweating and heat intolerance Chronic fatigue, sleepiness and exhaustion Constricted pupils Nausea Low blood pressure Hallucination Headache Vomiting Cardiac arrhythmia[24] Anorexia Weight gain Sudden Death Gynecomastia Memory loss Stomach pains Dry mouth Perspiration Flushing Itching Difficulty urinating Swelling of the hands, arms, feet, and legs Agitation Mood changes Blurred vision Insomnia Impotence Skin rash Seizures plz discontinue the medicine and take safer drugs like- diclofenac sodium ibuprofen hope for best by best regards DR G C OJHA