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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Taking Clonidine For Restless Leg Syndrome. Having Systemic Lupus Erythematosus Since Childhood. Treatment?

Hello, thank you for helping me. I am taking .3mg of clonidine for RLS. How long does it take to start working once taken? I have been on it for roughly five years; my dose was increased just recently to .3mg. OD
I have SLE since childhood. 10 years ago I was hospitalized for 4 years(still in and out of hospital) with chronic pancreatitis.
Was on 80mg Ms contin and have managed to decrease myself very slowly to 15md,OD. I have not had any obvious withdrawal symptoms. My sleep study before the morphine indicated severe RLS. However, since the decrease of my morphine the RLS had intensified severely.
I am just wondering if I am not taking it early enough at night to calm it down before sleeping. I take it at 7:30 pm each night, should I be taking it earlier? Does it need more time to kick in? I don't really understand what the half life means?
Thank you very much again for answering my question. Deb.
Sat, 7 Sep 2013
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Orthopaedic Surgeon 's  Response
Hello,
I have studied your case with diligence.

Half life means time in which half of drug is eliminated from body .
but its not related to start of effect of drug.
T 1/2 is important for start of effect of particular drug . clonodine works with in 10 to 15 min when taken.
You need to enhance your body immunity by meditation,immune herbs.learn various technique to induce sleep .

Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries.

Wishing you good health.

Take care
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Taking Clonidine For Restless Leg Syndrome. Having Systemic Lupus Erythematosus Since Childhood. Treatment?

Hello, I have studied your case with diligence. Half life means time in which half of drug is eliminated from body . but its not related to start of effect of drug. T 1/2 is important for start of effect of particular drug . clonodine works with in 10 to 15 min when taken. You need to enhance your body immunity by meditation,immune herbs.learn various technique to induce sleep . Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries. Wishing you good health. Take care