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T3N1M1 rectal cancer, multiple nodules, liver calcification, fever, no appetite

Hi, my dad is T3 N1M1 metastatic (in liver) rectal cancer patient. he 62 years old now. he s been through major surgery last year and a part of rectum and colon is removed and has been through 12 cycle chemo therapy through IV. the last CT scan conducted in last Nov says multiple nodules and calcification is seen in the liver. we were suggested to go for more chemo now oral chemo. dad denied for it. he is home and now having high fever upto 105 F , he has no appetite at all, doesn t feel any taste by his tongue when he tries to eat . can you Please tell me what is going on and what are we supposed to do, Please? he also has sensation that something is running through his veins all over his body and can t sleep properly.
Asked On : Fri, 11 May 2012
Answers:  2 Views:  632
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Gastroenterologist, Surgical 's  Response
Dear Krostha,
Your father has rectal cancer with liver metastasis at the time of rectal surgery and has received chemotherapy injections. Oral chemotherapy is very good option to consider for re-start second cycle of chemo. Family motivation may help your father to restart new chemotherapy.
High grade fever is an other cause for ill-health of your father and it is usually not due to cancer spread to liver. Other causes of infection should be rule-out. Rarely liver tumor nodule may get infected and may cause fever. Once fever is get controlled, overall well being of your father will definitely improve. So consult your surgeon/physician to look for cause of fever.
Wish to have good health for you father.
Answered: Fri, 11 May 2012
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General & Family Physician Dr. Pavan Kumar Gupta's  Response
The liver is highly susceptible to metastasis.  Liver metastasis occurs when cancer spreads from another part of the body to the liver. Patients with colon, eye, stomach, pancreatic, breast or lung cancer are at highest risk for developing liver metastasis, and should be examined regularly by a medical professional to prevent secondary liver cancers from forming. While liver metastasis does not always display noticeable symptoms, some patients with liver metastasis have sweats, abdominal pain, weight loss, nausea and fevers. Depending on the severity and progression of the liver metastasis, patients may experience these symptoms or not. It is important for all cancer patients to see a doctor regularly since people with untreated liver metastasis live an average of just 8.7 months.Considerations

Sometimes the symptoms that appear from liver metastasis may be wrongly perceived as something entirely separate from the cancer. For example, sudden anorexia may be attributed to a psychological problem when, in fact, severe weight loss may actually be the result of an undiagnosed liver metastasis. Similarly, fevers, nausea and sweats may be chalked up to the flu when they are actually being caused by a liver metastasis. Always check with a doctor before dismissing symptoms as harmless. People with a history of cancer should be especially vigilant about discussing symptoms with a medical professional.

When liver metastasis becomes terminal, more noticeable and serious symptoms materialize. Jaundice and hepatic encephalopathy indicate that death is near. Once these symptoms appear, the liver metastasis has progressed too far and further medical treatment will likely be ineffective.

There is no curative treatment for liver metastasis. 

Your father should be under the guidance and treatment of the doctor.
Answered: Fri, 11 May 2012
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