Thanks for writing in.
At 415lbs, there is a good amount of weight your legs need to bear. As your primary health workup is normal for cancer, blood pressure and diabetes
and your fatigue
and shortness of breath
has gone away, it doesnt look serious. However there is a lot of weight that may be causing erosive changes in your knees. You can get yourself checked for liver and kidney
function tests just to be sure they are normal.
Hope this helps