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Suspected CIDP. Weakness in limbs. Collected spinal fluid. Prescribed Prednisone

Hi, very recently my husband got diagnosed as suspected CIDP . His arms and lags become very week. Doctor tapped the spine and collect the fluid, but found the protein level within normal limit. His muscles in arms become very loose, soft which is not looking normal. In the last 3 months, he fell down 3 times, which was manageable for any normal human being. I need to be sure about his health status and about the available treatment facility. Now, he has given prednisone with a high doze (60 mg/day).
Asked On : Sun, 25 Nov 2012
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Neurologist 's  Response
Nov 2013

Thank you for posting your query.

CIDP is characterised by weakness of both arms and legs. The affected limbs feel loose and symptoms progress over time. Nerve conduction studies show evidence of demyelination (damage of nerve covering called myelin sheath). CSF analysis shows high protein.

If there is any doubt in diagnosis, biopsy of the sural nerve (nerve located near ankle) is done.

For proven CIDP, high dose steroids are accepted as first line treatment. Cases that do not improve with steroids may be treated with immunoglobulin injections or plasma exchange.

Best wishes,
Dr Sudhir Kumar MD DM (Neurology)
Senior Consultant Neurologist
Answered: Tue, 18 Dec 2012
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