Hello You were taking diane 35 ( cyproterone ) for 10 years . Diane 35 is prescribed for hirsutism , acne , as oral contraceptive pills in female . While it is also advised in male . But as you mentioned that there is breaking of skin , so this may be due to the side effect of diane . But important thing you mentioned that weight is not decreasing . You didn t mention ,why you were taking this drug . As this is also advised in pcod cases, while pcod is the main reason of weight gain in young child bearing age group patient. You mentioned that you are , now taking treatment for acne and skin rash, so regular it. First of all for weight gain find out ,what is the reason. Get in ultrasound of both ovaries to rule out pcod as you are also having irregular bleeding ( main characteristic feature of pcod). Try to avoid spicy , greasy , pizza, burger, sweets as these are main reason of weight gain. I advise my patient to take ORLISTAT 120 mg twice in day on empty stomach for 6-12 months for weight reduction. But this drug must be taken under strict medical supervision , so consult a physician and get his opinion but before this consult a gynecologist and rule out pcod. Good luck.